Global Burden of Disease (GBD) study which was published at conducted in the year 1990 provided the mostfirst comprehensive measureestimate about the burden of 135 diseases, and ischemic heart diseases were ranked as the leading cause followed by cerebrovascular disease as the secondcerebrovascular disease was found to be the second most frequent cause of mortality after ischemic heart diseases. . During the past few decades, the database for GBD has significantly evolved and use advanced methodologies for modelling the range of conditions and their risk factors since 1988, covering two-thirds of the population. This vast database facilitated reasonably to estimate the stroke burden. In GBD 2016, a systematic analysis of global, regional and national burden of stroke was provided by the stroke collaborators according to the incidence, prevalence, deaths and disability-adjusted life years (DALYs)stroke collaborators provided a systematic analysis of global, regional and national burden of stroke in terms of incidence, prevalence, deaths and disability-adjusted life years (DALYs). Two-thirds of deaths were reported in developing countries in which 40% of the patients were below the age of 70 years. Also, cerebrovascular disease is is ranked as the leading cause of adult disability, and each year, millions of stroke survivors have to restrict their daily activities to adapt to the life. millions of stroke survivors have to adapt to a lifestyle with restricted activities of their day to day living. WHO has established four non communicable diseases (cardio vascular, diseases, cancer, diabetes, pulmonary diseases) that make people die prematurely, and four modifiable behavioral or lif
e style risk factors (tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol) and featured a 4×4 principle. This concept featured as best buy principle, for mass actions on life style risk factors as the most cost-effective means of prevention. .Regard toWith respect to stroke this is quite important as stroke has shares many common features with other non -communicable diseases. Further to this WHO also added hypertension and aAtrial fibrillation were also added in the action plan on NCD . Cerebrovascular disorders can be prevented to a large extent byand providing awarnessan entry point consideration for public health initiatives to minimize the global burden of stroke. Current trends suggest that the number of annual deaths will rise up climb to 6.7 million by 2021 without appropriate action. Definitive treatment of stroke is thrombolytic therapythrombolysis which has to be delivered within 4.5 hours hrs of symptom onset. .But the earlier treatment given, the better the outcomes.But earlier the treatment given better outcomes will be. Treatment of acute stroke as well as preventative measurements should be given at the same time equal weightage to reduce the burden of stroke. Stroke is not only life- threatening, but also disabling with significant impact on quality of life. SoSo, all possible efforts should be provided made to treat acute stroke patients in therapeutic window and precautionary measures to identify risk factors like atrial fibrillation at community level to prevent a potential threat. This project aims to identify potential causes and recommend necessary changes to facilitate timely delivery of thrombolytic therapy. thrombolysis treatment.